SKU: 15-0069
{"num_reviews":0,"url":"https://epicypher-c9.mybigcommerce.com/products/recombinant-proteins/histone-binding-domains/enl-yeats-domain-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"google","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""}],"gtin":null,"id":342,"can_purchase":true,"meta_description":"ENL YEATS Domain, Recombinant Human for Protein Binding and Inhibitor Screening Experiments","category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"AddThisServiceButtonMeta":"","main_image":null,"add_to_wishlist_url":"/wishlist.php?action=add&product_id=342","custom_fields":[{"id":"194","name":"Pack Size","value":"100 μg"},{"id":"195","name":"Internal Comment","value":"1 unit left, with special peptide terminus"},{"id":"196","name":"Internal Comment","value":"41 units of lot 6 in New Lot Rack in Psylocke, included in count"}],"sku":"15-0069","description":"<div><table width=\"100%\" border=\"0\" cellspacing=\"2\" cellpadding=\"2\"> <tbody> <tr valign=\"top\"> <td> <table width=\"95%\" border=\"0\" cellspacing=\"1\" cellpadding=\"1\"> <tbody> <tr> <td> <table width=\"100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\"> <tbody> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Type: </b>YEATS</span></span></td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Host: </b><em>E. coli</em></span></span> </td> </tr> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Mol Wgt.: </b>19 kDa</span></span> </td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Epitope Tag: </b>His</span></span> </td> </tr> </tbody> </table> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b><b>ENL YEATS Domain, Recombinant Human Description:</b></b> ENL YEATS Domain, Recombinant Human (MLLT1, LTG19, YEATS1, accession Q03111, amino acids 1 to 150) containing a C-terminal His tag, expressed in <em>E. coli.</em> The ENL protein is part of the super elongation complex regulating RNA Pol II transcription. A chromosomal translocation resulting in an MLL-ENL fusion is involved in pediatric Acute Lymphoblastic Leukemia. ENL YEATS Domain, Recombinant Human interacts specifically with histone H3 crotonylated at lysine 27 and to a lesser extent lysine 9. </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><b>ENL YEATS Domain, Recombinant Human Formulation:</b> Recombinant 6xHis-tagged protein at 1 mg/ml in 50 mM Tris-HCl pH 7.5, 200 mM NaCl, 20% glycerol.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><b>ENL YEATS Domain, Recombinant Human Storage and Stability:</b> Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><b>ENL YEATS Domain, Recombinant Human Application Notes:</b> ENL YEATS Domain, Recombinant Human is useful for protein binding and screening experiments examining crotonylated and acetylated protein substrates.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><b>References Using this Product:</b><br /> <br /> <br /> </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\">View technical datasheet for this product. <a href=\"/content/documents/tds/15-0069.pdf\" target=\"_new\"> <img src=\"/content/documents/tds/icon.png\" alt=\"15-0069 Datasheet\" width=\"30\" height=\"40\" /></a></span></span> </td> </tr> </tbody> </table> </td> <td> <table width=\"300\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\"> <tbody> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0069_protein_gel_web.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0069_protein_gel_web.jpg\" alt=\"15-0069 Protein Gel Data\" width=\"160\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><strong>Protein Gel Data:</strong> ENL YEATS Domain, Recombinant Human (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br /> <strong>(Click image to enlarge) </strong></span></span></p> <p></p> </td> </tr> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0069_interaction.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0069_interaction.jpg\" alt=\"15-0069 Protein Interaction Data\" width=\"160\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 11pt; \" class=\"Apple-style-span\"><strong>Protein Interaction Data:</strong> ENL YEATS Domain, Recombinant Human used in peptide binding studies to detect interactions with specific post-translational modifications using AlphaLISA. The identities of the peptides tested are listed on the X-axis. <br /> ac-acetylated <br /> cr-crotonylated<br /> <strong>(Click image to enlarge) </strong></span></span></p> <p></p> </td> </tr> </tbody> </table> </td> </tr> </tbody></table></div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$325.00","value":325,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"","page_title":"ENL YEATS Domain, Recombinant Human","cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"options":[],"related_products":[{"id":364,"sku":"15-0070","name":"ENL YEATS Domain, Y78A, Recombinant Human","url":"https://epicypher-c9.mybigcommerce.com/products/recombinant-proteins/histone-binding-domains/enl-yeats-domain-y78a-recombinant-human","availability":"","rating":0,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain 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Pack Size: 100 μg
