Histone H2AX, Recombinant Human
$135.00
SKU: 15-0307
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Histone H2AX is a histone variant that is incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AX is phosphorylated on serine 139 by the ATM and ATR kinases in response to DNA double strand breakage. Phosphorylated H2AX serves as a platform to recruit a number of DNA damage repair proteins, including BRCA1, NBS1 and MDC1. <br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Formulation:</b> 100 µg of lyophilized powder.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Storage and Stability:</b> Lyophilized proteins are stable for 2 years at -20°C from date of shipment. Reconstitute with sterile distilled water and aliquot to avoid repeated freezing and thawing. <span class=\"Apple-style-span\" style=\"font-size: 12pt; \"> Stable for 6 months at -80°C <span class=\"Apple-style-span\" style=\"font-size: 12pt; \">after reconstitution.</span></span><br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Application Notes:</b> Recombinant histone H2AX is suitable for enzyme assays and nucleosome reconstitution.<br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>References:</b><br /> <br /> </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\">View technical datasheet for this product. <a href=\"/content/documents/tds/15-0307.pdf\" target=\"_new\"> <img src=\"/content/documents/tds/icon.png\" alt=\"15-0307 Datasheet\" width=\"30\" height=\"40\" /></a></span></span> </td> </tr> </tbody> </table> </td> <td> <table width=\"100%\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\"> <tbody> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0307_gel_tds.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0307_gel_tds.jpg\" alt=\"15-0307 Gel and Purity QC Data\" width=\"114\" height=\"250\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><strong>QC Purity Data:</strong> Histone H2AX, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br /> <strong>(Click image to enlarge) </strong></span></span></p> </td> </tr> </tbody> </table> </td> </tr> </tbody></table></div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$135.00","value":135,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"","page_title":"Recombinant Human Histone H2AX Protein","cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"options":[],"related_products":[{"id":560,"sku":"16-1013","name":"Mononucleosomes (H2AX), Human Recombinant","url":"https://epicypher-c9.mybigcommerce.com/products/nucleosomes/mononucleosomes-h2ax-human-recombinant","availability":"","rating":0,"brand":{"name":null},"category":["Nucleosomes","Nucleosomes/Recombinant Nucleosomes (rNucs)","Nucleosomes/Variant Nucleosomes (vNucs)"],"summary":" Mononucleosomes (H2AX), Human Recombinant Description: ","image":null,"images":[],"date_added":"18th Jan 2024","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":394,"name":"Pack Size","value":"50 μg"}],"num_reviews":0,"weight":{"formatted":"0.01 Ounces","value":0.01},"demo":false,"add_to_cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php?action=add&product_id=560","price":{"without_tax":{"currency":"USD","formatted":"$475.00","value":475},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=560"},{"id":378,"sku":"16-0013","name":"Mononucleosomes (H2AX), Human Recombinant Biotinylated","url":"https://epicypher-c9.mybigcommerce.com/products/nucleosomes/mononucleosomes-h2ax-human-recombinant-biotinylated","availability":"","rating":0,"brand":{"name":null},"category":["Nucleosomes","Nucleosomes/Recombinant Nucleosomes (rNucs)","Nucleosomes/Variant Nucleosomes (vNucs)"],"summary":" Mononucleosomes (H2AX), Human 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","image":null,"images":[],"date_added":"18th Jan 2024","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":52,"name":"Pack Size","value":"100 μg"}],"num_reviews":0,"weight":{"formatted":"0.01 Ounces","value":0.01},"demo":false,"add_to_cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php?action=add&product_id=167","price":{"without_tax":{"currency":"USD","formatted":"$115.00","value":115},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=167"},{"id":315,"sku":"15-0312","name":"Histone H3.3, Recombinant Human","url":"https://epicypher-c9.mybigcommerce.com/products/recombinant-proteins/recombinant-histones/histone-h3-3-recombinant-human","availability":"","rating":0,"brand":{"name":null},"category":["Discontinued Products"],"summary":" ","image":null,"images":[],"date_added":"18th Jan 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data-sitekey=\"6LcjX0sbAAAAACp92-MNpx66FT4pbIWh-FTDmkkz\"></div><br/>"}},"bulk_discount_rates":[],"meta_keywords":"recombinant, recombinant protein, recombinant h2ax, histone H2A.X, histone H2AX, histone, H2A.X, H2AX, histone-H2AX, histone-H2A.X, histoneH2AX, histoneH2A.X, H2AX, h2A.X, -h2ax, -h2a.x, h2ax, h2A.X, pAb, polyclonal, H2AX P-S139, H2A histone family member X, Histone H2 Phospho Ser139, Histone H2 Phosphorylated Ser139, Histone H2 Phosphorylated Serine 139","show_quantity_input":1,"title":"Histone H2AX, Recombinant Human","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[]} Pack Size: 100 μg
{"num_reviews":0,"url":"https://epicypher-c9.mybigcommerce.com/products/recombinant-proteins/recombinant-histones/histone-h2ax-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"google","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""}],"gtin":null,"id":273,"can_purchase":true,"meta_description":"Recombinant Human Histone H2AX Protein for Enzyme Screening Assays","category":["Recombinant Proteins/Recombinant Histones"],"AddThisServiceButtonMeta":"","main_image":null,"add_to_wishlist_url":"/wishlist.php?action=add&product_id=273","custom_fields":[{"id":"150","name":"Pack Size","value":"100 μg"}],"sku":"15-0307","description":"<div><table width=\"100%\" border=\"0\" cellspacing=\"2\" cellpadding=\"2\"> <tbody> <tr valign=\"top\"> <td> <table width=\"95%\" border=\"0\" cellspacing=\"1\" cellpadding=\"1\"> <tbody> <tr> <td> <table width=\"100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\"> <tbody> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Type: </b>Histone</span></span> </td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Host: </b><em>E. coli</em></span></span> </td> </tr> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Mol Wgt.: </b>15 kDa</span></span> </td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Epitope Tag: </b>by product</span></span> </td> </tr> </tbody> </table> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><br /> <b>Histone H2AX, Recombinant Human Description:</b> Recombinant human histone H2AX (H2AFX, accession P16104) expressed in <em>E. coli</em> and purified by FPLC. Histone H2AX is a histone variant that is incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AX is phosphorylated on serine 139 by the ATM and ATR kinases in response to DNA double strand breakage. Phosphorylated H2AX serves as a platform to recruit a number of DNA damage repair proteins, including BRCA1, NBS1 and MDC1. <br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Formulation:</b> 100 µg of lyophilized powder.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Storage and Stability:</b> Lyophilized proteins are stable for 2 years at -20°C from date of shipment. Reconstitute with sterile distilled water and aliquot to avoid repeated freezing and thawing. <span class=\"Apple-style-span\" style=\"font-size: 12pt; \"> Stable for 6 months at -80°C <span class=\"Apple-style-span\" style=\"font-size: 12pt; \">after reconstitution.</span></span><br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Histone H2AX, Recombinant Human Application Notes:</b> Recombinant histone H2AX is suitable for enzyme assays and nucleosome reconstitution.<br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>References:</b><br /> <br /> </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\">View technical datasheet for this product. <a href=\"/content/documents/tds/15-0307.pdf\" target=\"_new\"> <img src=\"/content/documents/tds/icon.png\" alt=\"15-0307 Datasheet\" width=\"30\" height=\"40\" /></a></span></span> </td> </tr> </tbody> </table> </td> <td> <table width=\"100%\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\"> <tbody> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0307_gel_tds.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0307_gel_tds.jpg\" alt=\"15-0307 Gel and Purity QC Data\" width=\"114\" height=\"250\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><strong>QC Purity Data:</strong> Histone H2AX, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br /> <strong>(Click image to enlarge) </strong></span></span></p> </td> </tr> </tbody> </table> </td> </tr> </tbody></table></div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$135.00","value":135,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"","page_title":"Recombinant Human Histone H2AX Protein","cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"options":[],"related_products":[{"id":560,"sku":"16-1013","name":"Mononucleosomes (H2AX), Human Recombinant","url":"https://epicypher-c9.mybigcommerce.com/products/nucleosomes/mononucleosomes-h2ax-human-recombinant","availability":"","rating":0,"brand":{"name":null},"category":["Nucleosomes","Nucleosomes/Recombinant Nucleosomes (rNucs)","Nucleosomes/Variant Nucleosomes (vNucs)"],"summary":" Mononucleosomes (H2AX), Human Recombinant Description: ","image":null,"images":[],"date_added":"18th Jan 2024","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":394,"name":"Pack Size","value":"50 μg"}],"num_reviews":0,"weight":{"formatted":"0.01 Ounces","value":0.01},"demo":false,"add_to_cart_url":"https://epicypher-c9.mybigcommerce.com/cart.php?action=add&product_id=560","price":{"without_tax":{"currency":"USD","formatted":"$475.00","value":475},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=560"},{"id":378,"sku":"16-0013","name":"Mononucleosomes (H2AX), Human Recombinant Biotinylated","url":"https://epicypher-c9.mybigcommerce.com/products/nucleosomes/mononucleosomes-h2ax-human-recombinant-biotinylated","availability":"","rating":0,"brand":{"name":null},"category":["Nucleosomes","Nucleosomes/Recombinant Nucleosomes (rNucs)","Nucleosomes/Variant Nucleosomes (vNucs)"],"summary":" Mononucleosomes (H2AX), Human 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data-sitekey=\"6LcjX0sbAAAAACp92-MNpx66FT4pbIWh-FTDmkkz\"></div><br/>"}},"bulk_discount_rates":[],"meta_keywords":"recombinant, recombinant protein, recombinant h2ax, histone H2A.X, histone H2AX, histone, H2A.X, H2AX, histone-H2AX, histone-H2A.X, histoneH2AX, histoneH2A.X, H2AX, h2A.X, -h2ax, -h2a.x, h2ax, h2A.X, pAb, polyclonal, H2AX P-S139, H2A histone family member X, Histone H2 Phospho Ser139, Histone H2 Phosphorylated Ser139, Histone H2 Phosphorylated Serine 139","show_quantity_input":1,"title":"Histone H2AX, Recombinant Human","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[]} Pack Size: 100 μg
Current stock:
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